Funding awarded to P1vital Products will help transform treatment of depression using digital technology.
Posted 8th May 2019

Funding awarded to P1vital Products will help transform treatment of depression using digital technology.

The funding will enable a real-world evaluation of novel digital technology developed by PPL as part of a re-design of service provision for depression to make care more responsive and tailored to patient needs.

Nationally, over a million people are seeking or receiving treatment for depression at any one time. However, for patients, finding the right treatment can be difficult. The new 'walk-in' service will provide access to a range of healthcare professionals with specialist training and supported by PPL's innovative digital technology.

PPL is an award-winning company that conducts research into developing software products that improve the treatment of mental health conditions. Their flagship digital health system, i-spero®, provides a comprehensive online tool for the management of depression, including a personalised prediction of antidepressant response and ongoing symptom monitoring.

Using the i-spero® system, users are provided with personalised predictions, guided by a machine-learning algorithm, which can give an early indication if a treatment is not working. This can help doctors, working with their patients, to more quickly identify an effective treatment plan. Symptom monitoring can help patients be aware of and manage ongoing shifts in their mood, foster more effective communication with clinical teams, and enable more effective preventative measures if there is an indication of relapse.

Professor Guy Goodwin, Chief Medical Officer at P1vital and Senior Research Fellow at the University Of Oxford Department of Psychiatry, said: “Under current care approaches, patients experiencing depression can receive care in a piecemeal fashion with antidepressants prescribed in a trial-and-error process that can take many months to resolve. The technology embedded in the i-spero® system has the potential to accelerate the process of identifying effective treatments, and provides clinicians with the tools they need to provide more integrated care, ultimately helping patients get better faster and then stay well.”

Jonathan Kingslake, CEO at PPL, said: “This funding from Innovate UK will enable us to take our software, which we have seen perform well in structured research studies, and put it into the hands of real-world clinicians as they go about performing their daily clinical duties. We will have the opportunity to evaluate the performance and value of the technology, as part of a new and more comprehensive care pathway for patients with depression. This is an important step towards making our technology available to more people with mood disorders across the UK and abroad.”

Vanessa Short, CCG research lead at Canterbury and Coastal CCG, and GP at Newton Place in Kent, said: “Innovation in healthcare is our passion, and digital healthcare technologies have the potential to dramatically improve the way we can help our patients in a way that is affordable and sustainable. We are excited to work with P1vital Products and to bring our clinical experience to bear on the important problem of improving care pathways for those suffering from depression.”

PPL pioneers digital healthcare technologies that are developed to rigorous scientific and technical standards, working with scientists across academia, healthcare, and industry to revolutionize the way that mental health disorders are treated.

For more information, email: [email protected]

Disclaimer: Innovate UK is the new name for the Technology Strategy Board – the UK’s innovation agency. Taking a new idea to market is a challenge. Innovate UK funds, supports and connects innovative businesses through a unique mix of people and programmes to accelerate sustainable economic growth. For further information visit

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Find out how i-spero® can help your patients

If you are a primary care provider, or are responsible for the purchasing/commissioning of primary care or specialist mental health services we would welcome a discussion.